購(gòu)物車
幫助
021-54845833/15800441009
中文名稱：兔抗CCR5多克隆抗體
英文名稱： Anti-CCR5 rabbit polyclonal antibody
別 名： CKR5; CCR-5; CD195; CKR-5; CCCKR5; CMKBR5; IDDM22; CC-CKR-5
相關(guān)類別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
抗 原： CCR5
反應(yīng)種屬： Human, Mouse
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
|
Background: |
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. |
|
Applications: |
ELISA, IHC |
|
Name of antibody: |
CCR5 |
|
Immunogen: |
Synthetic peptide of human CCR5 |
|
Full name: |
chemokine (C-C motif) receptor 5 (gene/pseudogene) |
|
Synonyms： |
CKR5; CCR-5; CD195; CKR-5; CCCKR5; CMKBR5; IDDM22; CC-CKR-5 |
|
SwissProt: |
P51681 |
|
ELISA Recommended dilution: |
1000-5000 |
|
IHC positive control: |
Human Lymphoma and Human liver cancer |
|
IHC Recommend dilution: |
25-100 |
