兔抗CCR6多克隆抗體

Background:

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene.

Applications:

ELISA, IHC

Name of antibody:

CCR6

Immunogen:

Synthetic peptide of human CCR6

Full name:

chemokine (C-C motif) receptor 6

Synonyms：

BN-1; DCR2; DRY6; CCR-6; CD196; CKRL3; GPR29; CKR-L3; CMKBR6; GPRCY4; STRL22; CC-CKR-6; C-C CKR-6

SwissProt:

P51684

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human breast cancer and Human thyroid cancer

IHC Recommend dilution:

20-100