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  • SIAH1 抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW4920
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存：20
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中文名稱： SIAH1 抗原（重組蛋白）

英文名稱： SIAH1 Antigen (Recombinant Protein)

別     名： siah E3 ubiquitin protein ligase 1; SIAH1A

儲(chǔ)     存： 冷凍（-20℃）

相關(guān)類別：抗原

概      述

Fusion protein corresponding to a region derived from 1-282 amino acids of human SIAH1

技術(shù)規(guī)格

Full name:

siah E3 ubiquitin protein ligase 1

Synonyms:

SIAH1A

Swissprot:

Q8IUQ4

Gene Accession:

BC035562

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008]