兔抗CDC42EP5多克隆抗體

Background:

Cell division control protein 42 (CDC42), a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to CDC42 and regulate its function negatively. The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding. The protein may also play a role in septin organization and inducing pseudopodia formation in fibroblasts

Applications:

WB

Name of antibody:

CDC42EP5

Immunogen:

Synthesized peptide derived from N-terminal of human BORG3.

Full name:

CDC42 effector protein (Rho GTPase binding) 5

Synonyms：

CEP5; Borg3

SwissProt:

Q6NZY7

WB Predicted band size:

15 kDa

WB Positive control:

Jurkat cells lysate

WB Recommended dilution:

500-3000