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  • WFS1 抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW6549
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:20
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中文名稱: WFS1 抗原(重組蛋白)

英文名稱: WFS1 Antigen (Recombinant Protein)

別     名: Wolfram syndrome 1 (wolframin); WFS; WFRS; WFSL; CTRCT41

相關(guān)類別:抗原

儲(chǔ)     存: 冷凍(-20℃)

概     述

Fusion protein corresponding to a region derived from 691-890 amino acids of human WFS1

技術(shù)規(guī)格

Full name:

Wolfram syndrome 1 (wolframin)

Synonyms:

WFS; WFRS; WFSL; CTRCT41

Swissprot:

O76024

Gene Accession:

BC030130

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta-cell lines. Mutations in this gene are associated with Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), an autosomal recessive disorder. The disease affects the brain and central nervous system. Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6), also known as DFNA14 or DFNA38. Alternatively spliced transcript variants have been found for this gene.