小鼠抗CD4單克隆抗體

Background:

This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010].

Applications:

WB, IHC

Name of antibody:

CD4

Immunogen:

Fusion protein of human CD4

Full name:

CD4 molecule (CD4), transcript variant 1

Synonyms:

CD4mut

SwissProt:

P01730

IHC positive control:

human lymphoma tissue and human tonsil tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

51 kDa

WB Positive control:

HepG2, Hela, A549, COS7, Jurkat, MCF-7 cell lysates

WB Recommended dilution:

1000-5000