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    • 品牌 : 通蔚生物
    • 目錄號 : TW7222
    • 應用 : 僅限于科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
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中文名稱：小鼠抗IPO5單克隆抗體

英文名稱： Anti-IPO5 mouse monoclonal antibody
別      名： importin 5; IMB3; Pse1; imp5; KPNB3; RANBP5
相關類別： 一抗

儲      存： 冷凍（-20℃）
宿      主： Mouse

抗      原： IPO5
反應種屬： Human, Mouse
標  記 物： Unconjugate

克隆類型： mouse monoclonal


技術規(guī)格

Background:

Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.

Applications:

WB

Name of antibody:

IPO5

Immunogen:

Fusion protein of human IPO5

Full name:

importin 5

Synonyms:

IMB3; Pse1; imp5; KPNB3; RANBP5

SwissProt:

O00410

WB Predicted band size:

124 KD

WB Positive control:

A549, Hela, Jurkat, Raji cell, Mouse brain tissue lysates

WB Recommended dilution:

200-1000