抗 原: HSD3B7
儲(chǔ) 存: 冷凍(-20℃)
反應(yīng)種屬: Human, Mouse, Rat
標(biāo) 記 物: Unconjugate
技術(shù)規(guī)格
Background: |
This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene. |
Applications: |
ELISA, IHC |
Name of antibody: |
HSD3B7 |
Immunogen: |
Fusion protein of human HSD3B7 |
Full name: |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 |
Synonyms: |
CBAS1; PFIC4; SDR11E3 |
SwissProt: |
Q9H2F3 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human prostate cancer and human brain |
IHC Recommend dilution: |
50-200 |