兔抗HTRA3多克隆抗體

Background:

HtrA3, also known as PRSP (pregnancy-related serine protease), is a 453 amino acid secreted protein that contains one PDZ domain, one Kazal-like domain and one IGFBP N-terminal domain. Widely expressed with particularly high expression in ovary, heart, placenta and bladder, HtrA3 functions as a probable serine protease that is thought to play an important role in placental development. HtrA3 is downregulated in ovarian tumors, suggesting an alternative role in tumor suppression. HtrA3 exists as two alternatively spliced isoforms, designated short and long. The gene encoding HtrA3 maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes.

Applications:

ELISA, IHC

Name of antibody:

HTRA3

Immunogen:

Synthetic peptide of human HTRA3

Full name:

HtrA serine peptidase 3

Synonyms：

Prsp; Tasp

SwissProt:

P83110

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

50-200