歡迎來(lái)到上海通蔚！

021-54845833/15800441009

品質(zhì)保證 · 通蔚試劑

當(dāng)前位置: 首頁(yè) > 科研產(chǎn)品 > 科研抗體 > 其他抗體 > BCAS2抗原（重組蛋白）

產(chǎn)品中心

  • BCAS2抗原（重組蛋白）

    規(guī)格：
    數(shù)量：

    購(gòu)買數(shù)量

    價(jià)格：￥
    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW16170
    • 應(yīng)用 : 僅限于科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存：60
  • 商品詳情
  • 參考文獻(xiàn)
  • 說(shuō)明書下載
  • 商品評(píng)論0
  • 相關(guān)產(chǎn)品

中文名稱： BCAS2抗原（重組蛋白）

英文名稱： BCAS2 Antigen (Recombinant Protein)

別     名： DAM1; SPF27; Snt309

儲(chǔ)     存： 冷凍（-20℃）

相關(guān)類別： 抗原

概     述

Full length fusion protein

技術(shù)規(guī)格

Full name:

breast carcinoma amplified sequence 2

Synonyms:

DAM1; SPF27; Snt309

Swissprot:

O75934

Gene Accession:

BC005285

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

BCAS2 (breast carcinoma amplified sequence 2), also designated DAM1 (DNA amplified in mammary carcinoma 1 protein) or spliceosome-associated SPF 27, is a ubiquitously expressed nuclear protein that was originally identified as being overexpressed in various breast cancer cell lines. BCAS2 is now known to be a component of the spliceosome, participating in the removal of introns from mRNA precursors. BCAS2 specifically interacts (in a ligand-independent manner) with TR∫ (thyroid hormone receptor beta), ER? (estrogen receptor alpha), ER∫, PR (progesterone receptor), and PPAR? (Peroxisome proliferator-activated receptor gamma). BCAS2 functions as an ER coactivator and is capable of enhancing ER-mediated transcription. This suggests that BCAS2 is involved in the development of breast cancer.