兔抗NKX2-1多克隆抗體

Background:

This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TFF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription.

Applications:

ELISA, WB

Name of antibody:

NKX2-1

Immunogen:

Synthetic peptide of human NKX2-1

Full name:

NK2 homeobox 1

Synonyms：

BCH, BHC, NK-2, TEBP, TTF1, NKX2A, TITF1, TTF-1, NKX2.1

SwissProt:

P43699

ELISA Recommended dilution:

1000-5000

WB Predicted band size:

42 kDa

WB Positive control:

Mouse lung tissue

WB Recommended dilution:

200-1000